Assoc. Prof. Dr. Oğuz Büyükkileci

Research Interests

  • Industrial biotechnology and microbiology
  • Bio-based products
  • Valorization of agro-food wastes
  • Prebiotics and plant-based polymers

Thesis Supervised


  1. KEVSER SABANCI, (active). In vitro human gut fermentation of dietary fibers and investigation of possible health effects of by-products
  2. NÜKET POLAT, (active). Encapsulation of therapeutic agents within xylan nanoparticles dispersed in chitosan scaffold for colon specific and dose regulated delivery
  3. SÜREK ECE, (2017). Prebiotic oligosaccharide production from hazelnut wastes,

Master of Science

  1. SENEM YANAK, (active). Deep Eutectic Solvent Pretreatment of Food and Agricultural Wastes
  2. ŞEVVAL ŞEN, (active). Enhancement of Xylanase Activity in Xylooligosaccharides Production from Lignocellulosic Biomass
  3. KARANFİL GÜLPERİ (2021), Succinic acid production from lignocellulosic biomass by Actinobacillus succinogenes
  4. TEMELLİ NURAN (2021), Organosolv treatment for prebiotic oligosaccharide production from agro-food waste
  5. AHMAD BILAL, (2017). Extraction of phytochemicals from Scolymus hispanicus and determination of potential health effects
  6. POLAT NÜKET, (2017). Xylan degredation mechanism of human intestinal bacteria
  7. DOĞRU KEVSER, (2016). Pretreatment methods for valorization of hazelnut pruning wastes
  8. KURU GULTEN, (2013). Investigations on the effects of carbon sources and pH on exo-polygalacturonase production by Aspergillus sojae
  9. GENÇ BERNA, (2013). Utilization of orange peel extract for fungal enzyme production
  10. BAYRAK EMRAH, (2013). Utilization of wine waste for fermentative processes



  1. Development of a deep eutectic solvent-based process to produce xylooligosaccharides from lignocellulosic biomass.2021-2024. Funding agent: TÜBİTAK (1001).

  2. Organasolv Pretreatment for the enzymatic producton of xylooligosaccharides.2018-2019. Funding agent: TÜBİTAK (1002). Principal Investigator.

  3. Production of xylooligosaccharides with prebiotic potential from hazelnut wastes using autohydrolysis and enzymatic hydrolysis.2014-2017. Funding agent: TUBITAK (1001). Involved in COST Action FP1306. Principal Investigator.

  4. Synthesis of novel extractants and utilization in recovery of lactic acid from the production media by reactive extraction and extractive fermentation 2019-2022. Researcher. Funding agent: TUBITAK (1001). PI: Mustafa Esen Martı

  5. Pectin production from dried fig wastes, by-products and scraps: Optimization of pectin extraction and characterization of molecular, functional and health effects.2018-2021. Researcher. Funding agent: TUBITAK (1001). PI: Ahmet Yemenicioğlu

  6. Identification of phytochemicals with potential health effects and testing the effects in in vitro models 2016-2019. Researcher. Funding agent: Ministry of Agriculture and Forestry. PI: Şükrü Güleç

  7. Derecemization of benzoin by biotransformation and L-phenylacetylcarbinol synthesis 2006-2007. Funding agent: TUBİTAK (1001). PI: Haluk Hamamcı



  • FE312 Introduction to industrial microbiology
  • FE307 Nutritional biochemistry


  • FE538 Bioprocess engineering principles
  • IBT630 Lignocellulose Biotechnology



  1. Surek, Ece, Ali Oguz Buyukkileci, and Sirma Yegin (2021). Processing of hazelnut (Corylus avellana L.) shell autohydrolysis liquor for production of low molecular weight xylooligosaccharides by Aureobasidium pullulans NRRL Y–2311–1 xylanase. Industrial Crops and Products 161 (2021): 113212.

  2. Zeybek Nuket, Rastall Robert A., Buyukkileci Ali Oguz (2020). Utilization of xylan-type polysaccharides in co-culture fermentations of Bifidobacterium and Bacteroides species. Carbohydrate Polymers, 236,  116076.

  3. Buyukkileci Ceylan, Batur Ayşem, Buyukkileci Ali Oguz, Hamamcı Haluk (2019).  Temperature and Glycerol Formation: A Proposal to Explain the Causal Relationship Based on Glycolytic Enzyme Activities.  American Journal of Enology and Viticulture, 70(2), 155-161., Doi: 10.5344/ajev.2018.18068

  4. Sabancı Kevser, Buyukkileci Ali Oguz, (2018).  Comparison of liquid hot water, very dilute acid and alkali treatments for enhancing enzymatic digestibility of hazelnut tree pruning residues.  Bıoresource Technology, 261, 158-165., Doi: 10.1016/j.biortech.2018.03.136

  5. Sürek Ece, Buyukkileci Ali Oguz (2018).  Kritik altı su ile fındık atıklarından antioksidan bileşiklerin ekstraksiyonu.  Gıda, 43(2), Doi: 10.15237/gida.GD17104

  6. Emrah Bayrak, Buyukkileci Ali Oguz (2018).  Utilization of white grape pomace for lactic acid production.  GIDA, 43(1), 129-138.

  7. Yeğin Sırma, Buyukkileci Ali Oguz, Sargın Sayıt, Göksungur Mehmet Yekta (2017).  Exploitation of Agricultural Wastes and By-Products for Production of Aureobasidium pullulans Y-2311-1 Xylanase: Screening, Bioprocess Optimization and Scale Up.  Waste and Bıomass Valorızatıon, 8(3), 999-1010., Doi: 10.1007/s12649-016-9646-6

  8. Sürek Ece, Buyukkileci Ali Oguz (2017).  Production of xylooligosaccharides by autohydrolysis of hazelnut (Corylus avellana L.) shell.  Carbohydrate Polymers, 174(null), 565-571., Doi: 10.1016/j.carbpol.2017.06.109

  9. Buyukkileci Ali Oguz, Marcelo Fernandez Lahore, Canan Tari (2015).  Utilization of orange peel  a food industrial waste  in the production of exo polygalacturonase by pellet forming Aspergillus sojae.  Bioprocess and Biosystems Engineering, 38(4), 749-760., Doi: 10.1007/s00449-014-1315-1

  10. Yeğin Sırma, Buyukkileci Ali Oguz (2015).  Mikrobiyal Ksilanazlar ve Gıda Endüstrisinde Kullanım Alanları.  Akademik Gıda, 13(4), 316-325.

  11. Can Ucuncu, Canan Tari, Demir Hande, Buyukkileci Ali Oguz, Banu Ozen (2013).  Dilute Acid Hydrolysis of Apple  Orange  Apricot and Peach Pomaces as Potential Candidates for Bioethanol Production.  Journal of Biobased Materials and Bioenergy, 7(3), 376-389., Doi: 10.1166/jbmb.2013.1361 (Yayın No: 2263023)

  12. Buyukkileci Ali Oguz,Tarı Canan,Fernandez Lahore Marcelo (2011).  Enhanced production of exo polygalacturonase from agro based products by Aspergillus sojae.  Bioresources, 6(3), 3452-3468. (Yayın No: 835255)

  13. Buyukkileci Ali Oguz, Yücel Ayşe Meral, Hamamcı Haluk (2006).  Lactate and ethanol productions by Rhizopus oryzae ATCC 9363 and activities of related pyruvate branch point enzymes.  Journal of Bioscience and Bioengineering, 102(5), 464-466., Doi: 10.1263/jbb.102.464 (Technical note)

  14. Buyukkileci Ali Oguz, Harsa Hayriye Şebnem (2004).  Batch production of L(+)-lactic acid from whey by Lactobacillus casei NRRL B 441.  Journal of Chemical Technology  Biotechnology, 79(9), 1036-1040., Doi: 10.1002/jctb.1094


  1. Polat Nuket, Buyukkileci Ali Oguz (2018).  Xylan degradation by colonic bacteria.  COST Action FP1306, 4th Workshop Valorization of lignocellulosic biomass side streams for sustainable production of chemicals, materials  fuels using low environmental impact technologies, Selanik, Greece (oral)

  2. Yeğin Sırma, Buyukkileci Ali Oguz (2017).  Microbial production of enzymes from lignocellulosic food waste.  3rd International Congress on Food and Biosystem Engineering, Rodos, Greece (oral)

  3. Doğru Kevser, Buyukkileci Ali Oguz (2017).  Different pretreatments for valorızatıon of hazelnut prunıng wastes.  FABE 2017 3nd Internatıonal Conference on Food and Biosystem Engineering, Rodos, Greece (oral)

  4. Sürek Ece,Doğru Kevser,Buyukkileci Ali Oguz (2017).  Valorization of walnut shells by liquid hot water treatment(autohydrolysis).  International Conference on Agriculture, Forest, Food Sciences And Technologies, Nevşehir, Turkey (oral)

  5. Ahmad Bilal, Buyukkileci Ali Oguz, Güleç Şükrü (2017).  Extraction, characterization of phytochemicals from medicinal plants and determination of their anti-carcinogenic effects.  International Students Science Conference, İzmir, Turkey (oral)

  6. Sürek Ece, Yeğin Sırma, Buyukkileci Ali Oguz (2017).  Enzymatic processing of hazelnut shell autohydrolysis liquor for production of prebiotic xylooligosaccharides.  COST Action FP1306 3rd Workshop on Valorization of lignocellulosic biomass side streams for sustainable production of chemicals, materials  fuels using low environmental impact technologies, Terromolinos, Spain (oral)

  7. Buyukkileci Ali Oguz, Sürek Ece, Doğru Kevser, Yeğin Sırma (2016).  Valorization of hazelnut wastes by production of prebiotic oligosaccharide and bioethanol.  Food Factor I – Barcelona Conference,Spain (oral)

  8. Sürek Ece, Buyukkileci Ali Oguz (2015).  Autohydrolysis of hazelnut shell for xylooligosaccharide production.  EurofoodChem XVIII, Madrid Spain (oral)

  9. Buyukkileci Ali Oguz, Tarı Canan, Fernandez-Llahore Marcelo, Demir Hande, Göğüş Nihan (2010).  Optimization of Exo-Polygalacturonase Production from Orange Peel by Aspergillus sojae.  IBS 2010, Rimini Italy (poster)

  10. Buyukkileci Ali Oguz, Yücel Ayşe Meral, Hamamcı Haluk (2007).  Physiology of Rhizopus oryzae at limiting glucose concentrations.  Physiology of Yeast and Filamentous Fungi 3, Helsinki, Finland (poster)

  11. Buyukkileci Ali Oguz, Hamamcı Haluk, Yücel Ayşe Meral (2004).  Investigation of pyruvate branch point of Rhizopus oryzae by comparison of in vitro enzyme activities.  Physiology of Yeast and  Filamentous Fungi 2, Anglet, France (poster)

  12. Buyukkileci Ali Oguz, Harsa Hayriye Şebnem (2000).  Batch production of lactic acid from whey by free Lactobacillus casei NRRL B-441.  FOOD2000-Blacksea and Central Asian Symposium on Food Technology, Ankara, Turkey (oral)